Plasmacytoma (Solitary bone plasmacytoma, extramedullary plasmacytoma)

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Solitary bone and extramedullary plasmacytoma.

Less than 5% of patients with a plasma cell dyscrasia present with a single bone (SBP) or extramedullary plasmacytoma (EMP) without evidence of systemic disease (normocalcemia, absence of anemia, preservation of uninvolved immunoglobulins, or renal disease attributable to myeloma). Diagnosis requires biopsy confirmation of a monoclonal plasma cell infiltrate from a single site. The treatment of...

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A Review for Solitary Plasmacytoma of Bone and Extramedullary Plasmacytoma

Solitary plasmacytoma (SP) is characterized by a mass of neoplastic monoclonal plasma cells in either bone (SBP) or soft tissue without evidence of systemic disease attributing to myeloma. Biopsy confirmation of a monoclonal plasma cell infiltration from a single site is required for diagnosis. The common presentation of SBP is in the axial skeleton, whereas the extramedullary plasmacytoma (EMP...

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Guidelines on the diagnosis and management of solitary plasmacytoma of bone and solitary extramedullary plasmacytoma.

Most patients with plasma cell neoplasia have generalized disease at diagnosis, i.e. multiple myeloma (MM). However, a minority (<5%) of patients with plasma cell malignancies present with either a single bone lesion, or less commonly, a soft tissue mass, of monoclonal plasma cells: solitary bone plasmacytoma (SBP) or extramedullary plasmacytoma (SEP). SBP has a high risk of progression to MM a...

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Solitary Plasmacytoma of Bone

Solitary plasmacytoma (SP), histologically indistinguishable from multiple myeloma (MM), is a kind of malignant tumor characterized by the proliferation of monoclonal plasma cells. SP is an independent subtype of plasmacytoma, including extramedullary plasmacytoma and solitary plasmacytoma of bone (SPB) [1]. Most solitary plasmacytomas progress to MM, and are usually treated in the department o...

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Solitary Extramedullary Plasmacytoma of the Bladder

Plasmacytoma is a rare B-lymphocyte neoplastic disorder that usually presents as the generalized disease multiple myeloma. Less than 5% of the cases present as a solitary mass of monoclonal plasma cells in the bone or soft tissue. Although solitary extramedullary plasmacytoma (SEP) may arise in any organ, it rarely involves the urinary bladder. A 67-year-old male without a history of multiple m...

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ژورنال

عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology

سال: 2019

ISSN: 1768-3262

DOI: 10.4267/2042/69762